Dodging speeding cars, crazed cabbies and eight million cranky pedestrians is all in a day’s work for Wilee (Joseph Gordon-Levitt), the best of New York’s agile and aggressive bicycle messengers. It takes a special breed to ride the fixie – super lightweight, single-gear bikes with no brakes and riders who are equal part skilled cyclists and nutcases who risk becoming a smear on the pavement every time they head into traffic. But a guy who’s used to putting his life on the line is about to get more than even he is used to when his last envelope of the day – a routine „premium rush“ run – turns into a life or death chase through the streets of Manhattan.